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TB-500 (Thymosin Beta-4)

A comprehensive technical overview of TB-500, a synthetic peptide fraction renowned for its role in regulating Actin for tissue regeneration. This profile details its unique mechanisms of action, including angiogenesis, cell migration, and anti-inflammatory properties specifically targeting muscle, tendon, and ligament recovery. Includes 99% purity HPLC specifications and critical stability protocols for reconstituted research solutions.

Product Overview

Product Overview: TB-500 (Thymosin Beta-4)

Description:

TB-500 is a synthetic fraction of the naturally occurring peptide Thymosin Beta-4, which is present in virtually all human and animal cells. It is widely recognized for its potent regenerative properties, specifically its ability to promote tissue repair, enhance wound healing, and support recovery in muscles, tendons, and ligaments.

Key Specifications:

  • Concentration: 5 MG per vial.
  • Purity: ≥99% (HPLC tested).
  • Molecular Formula: C212H350N56O78S.
  • Format: Lyophilized (Freeze-dried) powder.

Mechanism of Action (MOA)

TB-500 operates primarily through its ability to regulate Actin, a vital cellular protein essential for muscle cell formation and cell motility:

1. Cell Migration: It facilitates the migration of cells to the site of injury to accelerate repair.

2. Angiogenesis: It promotes the formation of new blood vessels (angiogenesis) in damaged tissues, ensuring better nutrient and oxygen delivery.

3. Anti-inflammatory Action: It reduces inflammation in joints and tissues, minimizing recovery time and improving flexibility.

4. Tissue Regeneration: It plays a crucial role in dermal wound healing and the regeneration of muscle fibers after strenuous activity or injury.

Storage and Stability

To maintain the integrity and potency of the peptide, follow these storage guidelines:

  • Lyophilized Powder (Before Reconstitution): Store in a cool, dry place. For long-term storage, it is best kept in the refrigerator (2°C to 8°C) or freezer (-20°C).
  • Reconstituted Solution: Once mixed with Bacterostatic Water or Sterile Saline, the product must be refrigerated (2°C to 8°C).
  • Shelf Life: It is recommended to use the reconstituted solution within 7–10 days for maximum efficacy.
  • General Note: Keep away from direct sunlight, high temperatures, and avoid vigorous shaking of the vial after reconstitution.

Key Benefits for Research

  • Accelerated recovery of connective tissues (tendons/ligaments).
  • Enhanced muscle growth and endurance.
  • Improved flexibility and reduced joint stiffness.
  • Support for cardiovascular and neurological health in research models.

Disclaimer: This product is intended for laboratory research purposes only. Not for human consumption.

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